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Lorenzo also corrupts the Maldenmen to his aid, turning them into a rampaging Cult that uses Ithaqua as a pawn with the end goal of granting him freedom from his prison. Admittedly, the base game paints him as being an unstable psychopath already, but here he's the Greater-Scope Villain for the entire mod, using his Psychic Powers to partly break down the aforementioned Flemmel to the point where he embraces his identity of "Ithaqua" and becomes a rampaging monster.
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Ernest Flemmel is pretty galling, especially in how they basically use him as a glorified lab rat after he's sent to Parsons State Insane Asylum after he goes mad. While the base game doesn't exactly paint them as saints either (what with them testing FEV on poor Edgar Swann), their treatment of their former coworker Dr. (the Commonwealth Institute of Technology).